- Obstetricians & Gynecologists, Groton - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Office Supplies, Equipment & Office Furniture Stores, Groton
- Oil & Gas Exploration & Development, Groton - Oil Field Exploration, Monitoring & Remediation
- Oil Burners Services, Groton
- Oil Change & Lubrication, Groton - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Groton - Oil Companies
- Ophthalmologists, Groton - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Groton
- Opticians, Groton
- Optometrists, Groton - Eye Doctors, Physicians & Surgeons (Optometry)
- Optometry Clinics, Groton - Eye Clinics
- Oral Surgeon, Groton - Dentists - Oral & Maxillofacial Surgeons
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- Ornamental Nursery, Groton
- Ornamental Nursery Services, Groton
- Orthodontist, Groton - Teeth Straightening, Invisalign & Dental Braces
- Orthopedists, Groton - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Attorneys & Lawyers, Groton
- Other Attorneys & Lawyers, Groton
- Other Building Materials & Supplies, Groton
- Other Lawyers & Attorneys, Groton
- Other Lodging, Groton
- Outboard Motors, Groton
- Outpatient Services, Groton - Outpatient Care
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