- Safety Training Schools, Middlefield
- Salvage Yards, Junk Yards & Wrecker Service, Middlefield
- Sand Gravel & Aggregate, Middlefield
- Satellite & Cable TV Equipment & Systems Repair & Service, Middlefield
- Satellite TV Service, Middlefield
- Scientific & Laboratory Equipment & Instruments, Middlefield
- Secondary Schools, Middlefield
- Sheet Metal Contractors, Middlefield - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Middlefield
- Shopping & Shopping Services, Middlefield
- Siding Contractors, Middlefield - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Signs, Middlefield
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- Signs & Advertising Specialties Manufacturers, Middlefield
- Ski Centers, Middlefield
- Ski Resorts, Middlefield
- Snow Removal Services, Middlefield - Snow Plow Service
- Social Services & Welfare, Middlefield
- Special Interest Schools Or Instruction, Middlefield
- Specialty Animal Services, Middlefield
- Specialty Stores, Middlefield
- Sports Photographers, Middlefield
- Spray Painting & Finishing, Middlefield - Plastic, Furniture, Acrylic, Wood & Metal
- Staffing & Support Services, Middlefield
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